Efficient one-pot synthesis of 5-perfluoroalkylpyrazoles by cyclization of hydrazone dianions-Reference-Cited by-同舟云学术

Efficient one-pot synthesis of 5-perfluoroalkylpyrazoles by cyclization of hydrazone dianions

Published:2015 Issue:30 Volume:13 Page:8277-8290
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ngo Thang Ngoc¹²³⁴,Ejaz Syeda Abida⁵⁶⁷⁸,Hung Tran Quang¹²³⁴⁹,Dang Tuan Thanh¹²³⁴,Iqbal Jamshed⁵⁶⁷⁸,Lecka Joanna¹⁰¹¹¹²¹³¹⁴,Sévigny Jean¹⁰¹¹¹²¹³¹⁴,Langer Peter¹²³⁴¹⁵

Affiliation:

1. Institut für Chemie

2. Universität Rostock

3. 18059 Rostock

4. Germany

5. Centre for Advanced Drug Research

6. COMSATS Institute of Information Technology

7. Abbottabad

8. Pakistan

9. Institute of chemistry

10. Department of Microbiology-Infectiology and Immunology

11. Faculty of Medicine

12. Centre de Recherche du CHU de Québec – Université Laval

13. Québec

14. Canada

15. Leibniz Institut für Katalyse an der Universität Rostock e. V. (LIKAT)

Abstract

A highly selective and efficient method for the synthesis of 5-trifluoromethylated and 5-perfluoroalkylated pyrazoles has been developed which relies on the cyclization of hydrazine dianions with ethyl perfluorocarboxylates.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01151E

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