Synthesis, DNA binding affinity and anticancer activity of novel 4H-benzo[g][1,2,3]triazolo[5,1-c][1,4]oxazocines

Author:

Sastry K. N. Visweswara12345,Routhu Sunitha Rani12346,Datta Soma Gupta12346,Nagesh Narayana734,Babu Bathini Nagendra5894,Nanubolu Jagadeesh Babu10234,Kumar C. Ganesh1234,Maurya Ram Awatar111213144,Kamal Ahmed12345

Affiliation:

1. Division of Medicinal Chemistry and Pharmacology

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad-500007

4. India

5. Department of Medicinal Chemistry

6. Department of Biotechnology

7. CSIR-Centre for Cellular and Molecular Biology

8. National Institute of Pharmaceutical Education and Research

9. Hyderabad-500037

10. Centre for X-Ray Crystallography

11. Applied Organic Chemistry Group

12. Chemical Science & Technology Division

13. CSIR-North East Institute of Science and Technology

14. Jorhat

Abstract

Cancer therapeutics: a new class of anticancer heterocycles was synthesized.

Funder

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference70 articles.

1. B. M. Burke , G. M.Wilkes and K. C.Ingwersen, Cancer chemotherapy, Jones and Bartlett Publishers, 2001, p. 1

2. B. Sarter , B. M.Burke, G. M.Wilkes and K. C.Ingwersen, Cancer chemotherapy care plans handbook, Jones and Bartlett Publishers, 2001, p. 1

3. Cancer statistics, 2013

4. Cancer multidrug resistance: mechanisms involved and strategies for circumvention using a drug delivery system

5. Metabolic targets for cancer therapy

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