An environmentally responsible 3-pot, 5-step synthesis of the antitumor agent sonidegib using ppm levels of Pd catalysis in water
Author:
Affiliation:
1. Department of Chemistry and Biochemistry
2. University of California
3. Santa Barbara
4. USA
5. Upper Canada College
Abstract
Sonidegib is a representative example of a valued pharmaceutical prepared under environmentally responsible conditions.
Funder
National Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/GC/C9GC03495A
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1. Hedgehog Pathway as a Potential Intervention Target in Esophageal Cancer
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