An optimized purification process for porcine gastric mucin with preservation of its native functional properties-Reference-Cited by-同舟云学术

An optimized purification process for porcine gastric mucin with preservation of its native functional properties

Published:2016 Issue:50 Volume:6 Page:44932-44943
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Schömig Veronika J.¹²³⁴⁵,Käsdorf Benjamin T.⁶³⁴⁵,Scholz Christoph¹²³⁴⁵,Bidmon Konstantinia⁶³⁴⁵,Lieleg Oliver⁶³⁴⁵,Berensmeier Sonja¹²³⁴⁵

Affiliation:

1. Bioseparation Engineering Group

2. Department of Mechanical Engineering

3. Technical University of Munich

4. D-85748 Garching

5. Germany

6. Institute of Medical Engineering and Department of Mechanical Engineering

Abstract

The purification of porcine gastric mucin was optimized and key properties such as gel formation at acidic pH, lubrication behavior and interactions of mucins with charged molecules were preserved.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA07424C

Reference53 articles.

1. A. Allen , The structure and function of gastrointestinal mucus, in Basic Mechanisms of Gastrointestinal Mucosal Cell Injury and Protection, Baltimore, 1981

2. Mucin Biopolymers As Broad-Spectrum Antiviral Agents

3. Mucin dynamics and enteric pathogens

4. Porcine Gastric Mucin (PGM) at the Water/Poly(Dimethylsiloxane) (PDMS) Interface: Influence of pH and Ionic Strength on Its Conformation, Adsorption, and Aqueous Lubrication Properties

5. pH-Dependent Conformational Change of Gastric Mucin Leads to Sol-Gel Transition

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