Laser ablation-inductively coupled plasma-mass spectrometry for quantitative mapping of the copper distribution in liver tissue sections from mice with liver disease induced by common bile duct ligation

Author:

Costas-Rodríguez Marta12345ORCID,Van Acker Thibaut12345ORCID,Hastuti Agustina A. M. B.12345,Devisscher Lindsey6745ORCID,Van Campenhout Sanne6745,Van Vlierberghe Hans6745ORCID,Vanhaecke Frank12345ORCID

Affiliation:

1. Department of Analytical Chemistry

2. Ghent University

3. Campus Sterre

4. BE-9000 Ghent

5. Belgium

6. Department of Gastroenterology and Hepatology

7. Ghent University Hospital

Abstract

High-resolution LA-ICP-MS bioimaging was shown suitable for the quantitative visualization of the Cu distribution in fibrotic mouse liver tissues on a (sub-)cellular level.

Publisher

Royal Society of Chemistry (RSC)

Subject

Spectroscopy,Analytical Chemistry

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