Fe(iii)-Catalyzed synthesis of steroidal imidazoheterocycles as potent antiproliferative agents

Author:

Samanta Sadhanendu1234ORCID,Ghosh Asim Kumar1234,Ghosh Sumit1234,Ilina Anastasia A.5678,Volkova Yulia A.5678ORCID,Zavarzin Igor V.5678,Scherbakov Alexander M.910118,Salnikova Diana I.91011812,Dzichenka Yaraslau U.13141516ORCID,Sachenko Anton B.13141516,Shirinian Valerii Z.5678ORCID,Hajra Alakananda1234ORCID

Affiliation:

1. Department of Chemistry

2. Visva-Bharati (A Central University)

3. Santiniketan

4. India

5. N.D. Zelinsky Institute of Organic Chemistry

6. Russian Academy of Sciences

7. 119991 Moscow

8. Russia

9. Department of Experimental Tumor Biology

10. N.N. Blokhin National Medical Research Center of Oncology

11. 115522 Moscow

12. Lomonosov Moscow State University

13. Institute of Bioorganic Chemistry of NAS of Belarus

14. Laboratory of Protein Engineering

15. Minsk

16. Republic of Belarus

Abstract

An efficient and practical method has been developed for the synthesis of steroidal imidazo[1,2-a]pyridines as potent antiproliferative agentsviaFeCl3-catalyzed oxidative amination in high yields.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Russian Foundation for Basic Research

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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