Synthesis and X-ray study of dispiro 8-nitroquinolone analogues and their cytotoxic properties against human cervical cancer HeLa cells-Reference-Cited by-同舟云学术

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Synthesis and X-ray study of dispiro 8-nitroquinolone analogues and their cytotoxic properties against human cervical cancer HeLa cells

Published:2019 Issue:3 Volume:10 Page:439-449
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Shyamsivappan Selvaraj¹²³⁴^ORCID,Vivek Raju⁵⁶⁷⁴^ORCID,Saravanan Arjunan⁸⁹³⁴,Arasakumar Thangaraj¹²³⁴,Subashini Gopalan¹⁰¹¹³⁴,Suresh Thangaraj¹²³⁴^ORCID,Shankar Ramasamy¹²²³⁴,Mohan Palathurai Subramaniam¹²³⁴

Affiliation:

1. School of Chemical Sciences

2. Bharathiar University

3. Coimbatore

4. India

5. Chemical Biology

6. Rajiv Gandhi Centre for Biotechnology

7. Thiruvananthapuram

8. DRDO-BU CLS

9. Bharathiar University Campus

10. Department of Chemistry

11. P.S.G.R. Krishnammal College For Women

12. Department of Physics

Abstract

A series of unique dispiro 8-nitroquinolone analogues has been obtained through a one pot three-component reaction.

Funder

University Grants Commission

Bharathiar University

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C8MD00482J

Reference43 articles.

1. Design, synthesis and QSAR studies of dispiroindole derivatives as new antiproliferative agents

2. Asymmetrical 2,6-bis(benzylidene)cyclohexanones: Synthesis, cytotoxic activity and QSAR study

3. Mechanism-Based Target Identification and Drug Discovery in Cancer Research

4. Cancer statistics, 2014

5. 1,3-Dipolar Cycloaddition Reactions for the Synthesis of Novel Oxindole Derivatives and Their Cytotoxic Properties

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