New ecdysone receptor agonists: a computational approach for rational discovery of insecticides for crop protection

Author:

Singh Rahul12,Bhardwaj Vijay Kumar123,Das Pralay34ORCID,Purohit Rituraj123ORCID

Affiliation:

1. Structural Bioinformatics Lab, CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur, HP, 176061, India

2. Biotechnology division, CSIR-IHBT, Palampur, HP, 176061, India

3. Academy of Scientific & Innovative Research (AcSIR), Ghaziabad-201002, India

4. Natural Product Chemistry and Process Development, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, India

Abstract

Plant derived (C. deodara) in-house synthesized molecules with benzosuberene scaffolds as potential EcR agonists to target Hemiptera and Coleoptera.

Funder

Academy of Scientific and Innovative Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Industrial and Manufacturing Engineering,Process Chemistry and Technology,Energy Engineering and Power Technology,Biomedical Engineering,Chemical Engineering (miscellaneous),Chemistry (miscellaneous)

Reference41 articles.

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3. A.Retnakaran , P.Krell , Q.Feng and B.Arif , in Archives of Insect Biochemistry and Physiology , 2003 , vol. 54 , pp. 187–199

4. Nuclear receptors — a perspective from Drosophila

5. The heterodimeric ecdysteroid receptor complex in the brown shrimp Crangon crangon: EcR and RXR isoform characteristics and sensitivity towards the marine pollutant tributyltin

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