Ru(ii)-Peptide bioconjugates with the cppH linker (cppH = 2-(2′-pyridyl)pyrimidine-4-carboxylic acid): synthesis, structural characterization, and different stereochemical features between organic and aqueous solvents-Reference-Cited by-同舟云学术

Ru(ii)-Peptide bioconjugates with the cppH linker (cppH = 2-(2′-pyridyl)pyrimidine-4-carboxylic acid): synthesis, structural characterization, and different stereochemical features between organic and aqueous solvents

Published:2019 Issue:2 Volume:48 Page:400-414
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Battistin Federica¹²³⁴^ORCID,Siegmund Daniel⁵⁶⁷⁸⁹^ORCID,Balducci Gabriele¹²³⁴^ORCID,Alessio Enzo¹²³⁴^ORCID,Metzler-Nolte Nils⁵⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Chemical and Pharmaceutical Sciences

2. University of Trieste

3. 34127 Trieste

4. Italy

5. Inorganic Chemistry I – Bioinorganic Chemistry

6. Ruhr University Bochum

7. Faculty of Chemistry and Biochemistry

8. Universitätsstraße 150

9. 44801 Bochum

Abstract

Three new Ru(ii)-peptide bioconjugates were prepared in pure form and fully characterized. Unlike in DMSO-d₆, stable stereoisomers were found by NMR studies in D₂O.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C8DT03575J

Reference54 articles.

1. Highly Potent Antibacterial Organometallic Peptide Conjugates

2. Metal Complex-Peptide Conjugates: How to Modulate Bioactivity of Metal-Containing Compounds by the Attachment to Peptides

3. The development of ruthenium(ii) polypyridyl complexes and conjugates forin vitrocellular andin vivoapplications

4. Organometallic–Peptide Bioconjugates: Synthetic Strategies and Medicinal Applications

5. Small cationic antimicrobial peptides delocalize peripheral membrane proteins

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