Versatile naphthalimide tetrazines for fluorogenic bioorthogonal labelling

Author:

Graziotto Marcus E.12ORCID,Adair Liam D.12ORCID,Kaur Amandeep34ORCID,Vérité Pauline5,Ball Sarah R.3,Sunde Margaret34ORCID,Jacquemin Denis5ORCID,New Elizabeth J.124ORCID

Affiliation:

1. The University of Sydney, School of Chemistry, NSW, 2006, Australia

2. Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, NSW, 2006, Australia

3. The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health, NSW, 2006, Australia

4. The University of Sydney Nano Institute (Sydney Nano), The University of Sydney, NSW, 2006, Australia

5. CEISAM Lab, CNRS, Université de Nantes, Nantes, France

Abstract

New naphthalimide tetrazine probes permit fluorescent imaging of biomolecules in vitro and in living cells. They can be modified to provide previously unknown information about health and disease in biological systems.

Funder

Westpac Scholars Trust

Australian Research Council

University of Sydney

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

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