The influence of differently functionalized nanodiamonds on proliferation, apoptosis and EMT/MET phenomena in 2D and 3D tumor cell cultures-Reference-Cited by-同舟云学术

The influence of differently functionalized nanodiamonds on proliferation, apoptosis and EMT/MET phenomena in 2D and 3D tumor cell cultures

Published:2021 Issue:45 Volume:9 Page:9395-9405
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Shirley Anup James¹²,Schweeberg Sarah³,Waag Thilo³,Peindl Matthias²,Dandekar Gudrun²,Walles Heike²⁴,Jakob Franz⁵,Krueger Anke³⁶^ORCID,Ebert Regina¹^ORCID

Affiliation:

1. Bernhard-Heine-Center for Locomotion Research, Department of Musculoskeletal Tissue Regeneration, Julius-Maximilians-Universität Würzburg, Friedrich-Bergius-Ring 15, 97076 Würzburg, Germany

2. Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Röntgenring 11, 97070 Würzburg, Germany

3. Institute for Organic Chemistry, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg, Germany

4. Core Facility Tissue Engineering, Otto-v. Guericke University Magdeburg, Pfälzerstraße 2, 39106 Magdeburg, Germany

5. Bernhard-Heine-Center for Locomotion Research and Department for Functional Materials in Medicine and Dentistry, Brettreichstraße 11, 97074 Würzburg, Germany

6. Wilhelm Conrad Röntgen Center for Complex Materials (RCCM), Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg, Germany

Abstract

Three different nanodiamonds (ND-BA, NDprist, ND-BQ) were applied in 2D and 3D models to LNCaP prostate and MDA-MB-231 and MCF-7 breast cancer cells. Proliferation, apoptosis and expression of EMT/MET markers were analyzed by qPCR and Western Blot.

Funder

Volkswagen Foundation

Seventh Framework Programme

Bayerische Forschungsstiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB01739J

Reference56 articles.

1. On the history of the discovery of nanodiamond synthesis