Docking-based computational analysis of guava (<i>Psidium guajava</i>) leaves derived bioactive compounds as a coagulation factor IXa inhibitor-Reference-Cited by-同舟云学术

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Docking-based computational analysis of guava (Psidium guajava) leaves derived bioactive compounds as a coagulation factor IXa inhibitor

Published:2024 Issue:35 Volume:14 Page:25579-25585
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

De Luna Joseph G.¹^ORCID,Gonzales Shanahi Chelledie B.¹,Nuqui Jimuel Jan M.¹,Capinding Evalyn S.¹,Sacdalan Corazon D.¹

Affiliation:

1. Department of Chemistry, Technological University of the Philippines, Ayala Boulevard, Ermita, Manila, Philippines

Abstract

This study identifies bioactive compounds from guava leaves that inhibit coagulation factor IXa, highlighting their potential for therapeutic applications in anticoagulant drug development.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04709E

Reference32 articles.

1. Cardiovascular diseases (CVDs) , https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds) , accessed, 15 May, 2024

2. A.Dorgalaleh , M.Daneshi , J.Rashidpanah and E. R.Yasaghi , in Congenital Bleeding Disorders , ed. A. Dorgalaleh , Springer International Publishing , Cham , 2018 , pp. 3–26

3. Hemostasis and Thrombosis: Methods and Protocols , ed. E. J. Favaloro and G. Lippi , Springer New York , New York, NY , 2017 , vol. 1646

4. A Structure Based Study of Selective Inhibition of Factor IXa over Factor Xa

5. Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities

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