Re-examining the role of the gut microbiota in the conversion of the lipid-lowering statin monacolin K (lovastatin) into its active β-hydroxy acid metabolite
Author:
Affiliation:
1. Laboratory of Food & Health
2. Research Group on Quality
3. Safety and Bioactivity of Plant Foods
4. Department of Food Science and Technology
5. CEBAS-CSIC
Abstract
The inter-conversion between MK and MKA depends on the pH whereas MKA was unequivocally catabolised by the gut microbiota.
Funder
Ministerio de Economía y Competitividad
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2019/FO/C8FO02594K
Reference24 articles.
1. Development of matrix effect-free MISPE-UHPLC–MS/MS method for determination of lovastatin in Pu-erh tea, oyster mushroom, and red yeast rice
2. The Quantification of Monacolin K in Some Red Yeast Rice from Fujian Province and the Comparison of the Other Product
3. Lovastatin and Simvastatin - Inhibitors of HMG CoA Reductase and Cholesterol Biosynthesis
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