A rapid and clean synthetic approach to cyclic peptides via micro-flow peptide chain elongation and photochemical cyclization: synthesis of a cyclic RGD peptide-Reference-Cited by-同舟云学术

A rapid and clean synthetic approach to cyclic peptides via micro-flow peptide chain elongation and photochemical cyclization: synthesis of a cyclic RGD peptide

Published:2016 Issue:47 Volume:14 Page:11244-11249
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Mifune Yuto¹²³⁴⁵,Nakamura Hiroyuki¹²³⁴⁵,Fuse Shinichiro¹²³⁴⁵

Affiliation:

1. Laboratory for Chemistry and Life Science

2. Institute of Innovative Research

3. Tokyo Institute of Technology

4. Yokohama 226-8503

5. Japan

Abstract

A cyclic RGD peptide was efficiently synthesized based on micro-flow, triphosgene-mediated peptide chain elongation and micro-flow photochemical macrolactamization.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB02391F

Reference58 articles.

1. Designing peptide receptor agonists and antagonists

2. Recent Progress of the Synthetic Studies of Biologically Active Marine Cyclic Peptides and Depsipeptides

3. Round and Round we Go: Cyclic Peptides in Disease

4. The Future of Peptide-based Drugs

5. The Emergence of Cyclic Peptides: The Potential of Bioengineered Peptide Drugs

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