Characterization and application of fluidic properties of trinucleotide repeat sequences by wax-on-plastic microfluidics-Reference-Cited by-同舟云学术

Characterization and application of fluidic properties of trinucleotide repeat sequences by wax-on-plastic microfluidics

Published:2020 Issue:4 Volume:8 Page:743-751
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Qamar Ahmad Zaman¹²³⁴,Asefifeyzabadi Narges¹²³⁴,Taki Motahareh¹²³⁴,Naphade Swati⁵⁶⁴,Ellerby Lisa M.⁵⁶⁴,Shamsi Mohtashim Hassan¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry & Biochemistry

2. Southern Illinois University at Carbondale

3. Carbondale

4. USA

5. The Buck Institute for Research on Aging

6. Novato

Abstract

This work demonstrates sequence directed flexibility of neurodegenerative trinucleotide repeat sequences can be translated into distinct capillary flow using wax-on-plastic microfluidics and used to detect microsatellite repeat expansions diseases.

Funder

National Science Foundation

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/C9TB02208B

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