Anti-proliferative activities of flavone–estradiol Stille-coupling adducts and of indanone-based compounds obtained by SnCl4/Zn-catalysed McMurry cross-coupling reactions

Author:

Pathe Gulab Khushalrao1234,Konduru Naveen K.1234,Parveen Iram1234,Ahmed Naseem1234

Affiliation:

1. Department of Chemistry

2. Indian Institute of Technology Roorkee

3. Roorkee-247 667

4. India

Abstract

Flavone–estradiol adducts and indanophen based tamoxifen analogs are synthesized using SnCl4–Zn reagent via McMurry reaction and evaluated in human cervical (HeLa) and breast cancer cells (MCF-7 and MDA-MB-231) for the anti-proliferative activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference63 articles.

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2. Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β

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4. Alternatives to estrogen

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