Regioselective synthesis of 3-nitroindoles under non-acidic and non-metallic conditions

Author:

Zhang Hua12ORCID,Su Rong-Chuan12ORCID,Qin Yu-Li12,Wang Xiao-Juan3,Chen Dan12,Liu Xiao-Rong12,Jiang Yu-Xin12,Zhao Peng12ORCID

Affiliation:

1. Department of Pharmacology, North Sichuan Medical College, Nanchong 637100, China

2. Institute of Materia Medica of North Sichuan Medical College, China

3. Department of Innovation & Entrepreneurship of NSMC, China

Abstract

An electrophilic substitution reaction, without acid and metal, of indole with ammonium tetramethylnitrate for accessing 3-nitroindole has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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