Simple, yet powerful methodologies for conformational sampling of proteins-Reference-Cited by-同舟云学术

Simple, yet powerful methodologies for conformational sampling of proteins

Published:2015 Issue:9 Volume:17 Page:6155-6173
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Harada Ryuhei¹²³⁴⁵,Takano Yu⁵⁶⁷⁴⁸,Baba Takeshi⁹¹⁰¹¹⁴,Shigeta Yasuteru¹²³⁴⁵

Affiliation:

1. Center for Computational Sciences

2. University of Tsukuba

3. Tsukuba

4. Japan

5. JST

6. CREST

7. Kawaguchi

8. Institute Protein Research

9. Department of Materials Engineering Science

10. Osaka University

11. Toyonaka

Abstract

This feature article reviews four different conformational sampling methods for proteins recently developed by us. We here deal with protein folding of small proteins, large amplitude domain motion of T4 lysozyme, and induced-fit motion of a loop region after substrate binding using our methods.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CP/C4CP05262E

Reference107 articles.

1. Reduced Native State Stability in Crowded Cellular Environment Due to Protein–Protein Interactions

2. Protein Crowding Affects Hydration Structure and Dynamics

3. How Fast-Folding Proteins Fold