An efficient direct phosphinylation and alkylation of ketones to construct C–P and C–C bonds: access to α,α-disubstituted γ-ketophosphine oxides-Reference-Cited by-同舟云学术

An efficient direct phosphinylation and alkylation of ketones to construct C–P and C–C bonds: access to α,α-disubstituted γ-ketophosphine oxides

Published:2023 Issue:2 Volume:10 Page:410-415
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wei Xiao-Hong¹^ORCID,Wang Xiao-Hong¹,Bai Chun-Yuan¹,Xue Ya-Wen¹,Zhang Ping¹,Wang Yan-Bin¹,Su Qiong¹

Affiliation:

1. Key Laboratory of Environment-Friendly Composite Materials of the State Ethnic Affairs Commission, Key Laboratory for Utility of Environment-Friendly Composite Materials and Biomass in University of Gansu Province, Gansu Provincial Biomass Function Composites Engineering Research Center, College of Chemical Engineering, Northwest Minzu University, No. 1, Northwest Xincun, Lanzhou, 730030, P. R. China

Abstract

The first example of an acid-promoted difunctionalization of ketones to construct C–P and C–C bonds via a phospha-aldol-elimination is described under metal- and solvent-free conditions.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Gansu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01749K

Reference52 articles.

1. Lewis Acid Induced ?-Alkylation of Carbonyl Compounds