Stereoselective synthesis of 2′-modified nucleosides by using ortho-alkynyl benzoate as a gold(i)-catalyzed removable neighboring participation group-Reference-Cited by-同舟云学术

Stereoselective synthesis of 2′-modified nucleosides by using ortho-alkynyl benzoate as a gold(i)-catalyzed removable neighboring participation group

Published:2017 Issue:4 Volume:7 Page:1814-1817
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ding Haixin¹²³⁴⁵,Li Chuang⁵⁶³⁴,Zhou Yirong⁵⁶³⁴,Hong Sanguo¹²³⁴,Zhang Ning¹²³⁴,Xiao Qiang⁵⁶³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Nanchang University

3. Nanchang

4. China

5. Jiangxi Key Laboratory of Organic Chemistry

6. Jiangxi Science & Technology Normal University

Abstract

ortho-Alkynyl benzoate was developed as a neighboring participation group in stereoselective synthesis of nucleosides, which could be removed using gold(i)-catalysis to afford 2′-OH nucleosides in high yield and selectivity.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA27790J

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