Identification of Gli-mediated transcription inhibitors through synthesis and evaluation of taepeenin D analogues-Reference-Cited by-同舟云学术

Identification of Gli-mediated transcription inhibitors through synthesis and evaluation of taepeenin D analogues

Author:

Antoniou A.¹²³⁴⁵,Chatzopoulou M.¹²³⁴⁵^ORCID,Bantzi M.⁶⁷⁸⁹,Athanassopoulos C. M.¹⁰¹¹¹²¹³⁵,Giannis A.⁶⁷⁸⁹,Pitsinos E. N.¹²³⁴⁵

Affiliation:

1. Natural Products Synthesis & Bioorganic Chemistry Laboratory

2. I.N.N

3. NCSR “Demokritos”

4. Athens

5. Greece

6. Universität Leipzig, Fakultät für Chemie und Mineralogie

7. Institut für Organische Chemie

8. 04103 Leipzig

9. Germany

10. Laboratory of Synthetic Organic Chemistry

11. Department of Chemistry

12. University of Patras

13. Patras

Abstract

Abietic acid derivatives related to taepeenin D were identified as new Hh pathway inhibitors that operate downstream of Smo.

Funder

General Secretariat for Research and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

Reference27 articles.

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