Pharmaceutical paroxetine-based organic salts of carboxylic acids with optimized properties: the identification and characterization of potential novel API solid forms-Reference-Cited by-同舟云学术

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Pharmaceutical paroxetine-based organic salts of carboxylic acids with optimized properties: the identification and characterization of potential novel API solid forms

Published:2019 Issue:24 Volume:21 Page:3668-3678
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Carvalho Paulo S.¹²³⁴^ORCID,Diniz Luan F.⁵⁶⁷⁴^ORCID,Tenorio Juan C.⁵⁶⁷⁴^ORCID,Souza Matheus S.⁵⁶⁷⁴^ORCID,Franco Chris H. J.⁸⁹¹⁰⁴^ORCID,Rial Rafael C.¹²³⁴,Warszawski de Oliveira Karla Regina¹²³⁴,Nazario Carlos E. D.¹²³⁴^ORCID,Ellena Javier⁵⁶⁷⁴^ORCID

Affiliation:

1. Instituto de Química

2. Universidade Federal do Mato Grosso do Sul

3. Campo Grande

4. Brazil

5. Instituto de Física de São Carlos

6. Universidade de São Paulo

7. 13560-970 - São Carlos

8. Departamento de Química

9. Universidade Federal de Juiz de Fora

10. Juiz de Fora

Abstract

Reacting paroxetine HCl with oxalic, maleic, fumaric and l-tartaric acids results in the formation of novel molecular salts.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CE/C8CE02076K

Reference39 articles.

1. Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges

2. Can the pharmaceutical industry reduce attrition rates?

3. Stability of pharmaceutical salts in solid oral dosage forms

4. Benefits of cocrystallisation in pharmaceutical materials science: an update

5. Use of pharmaceutical salts and cocrystals to address the issue of poor solubility

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