13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions-Reference-Cited by-同舟云学术

13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions

Published:2017 Issue:28 Volume:15 Page:6024-6032
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lohans Christopher T.¹²³⁴^ORCID,Wang David Y.¹²³⁴,Jorgensen Christian¹⁵⁶⁴^ORCID,Cahill Samuel T.¹²³⁴^ORCID,Clifton Ian J.¹²³⁴^ORCID,McDonough Michael A.¹²³⁴^ORCID,Oswin Henry P.⁷⁸⁹⁴,Spencer James⁷⁸⁹⁴,Domene Carmen¹²³⁴¹,Claridge Timothy D. W.¹²³⁴^ORCID,Brem Jürgen¹²³⁴,Schofield Christopher J.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Oxford

3. Oxford

4. UK

5. King's College London

6. London

7. School of Cellular and Molecular Medicine

8. University of Bristol

9. Bristol

Abstract

¹³C-NMR spectroscopy is a valuable tool for investigating the mechanisms of inhibitors of the clinically relevant OXA β-lactamases.