Minimal RNA self-reproduction discovered from a random pool of oligomers-Reference-Cited by-同舟云学术

Minimal RNA self-reproduction discovered from a random pool of oligomers

Published:2023 Issue:28 Volume:14 Page:7656-7664
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Mizuuchi Ryo¹²^ORCID,Ichihashi Norikazu³⁴⁵^ORCID

Affiliation:

1. Department of Electrical Engineering and Bioscience, Faculty of Science and Engineering, Waseda University, Shinjuku, Tokyo 162-8480, Japan

2. JST, FOREST, Kawaguchi, Saitama 332-0012, Japan

3. Komaba Institute for Science, The University of Tokyo, Meguro, Tokyo 153-8902, Japan

4. Department of Life Science, Graduate School of Arts and Science, The University of Tokyo, Meguro, Tokyo 153-8902, Japan

5. Universal Biology Institute, The University of Tokyo, Meguro, Tokyo 153-8902, Japan

Abstract

An RNA oligomer that self-reproducesviaprebiotically plausible chemistry was identified by examining short random RNA pools. The oligomer exhibits a potential for exponential self-reproduction, similar to the behavior of much larger ribozymes.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC01940C

Reference51 articles.

1. Origin of life: The RNA world

2. The antiquity of RNA-based evolution

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