Microwave-assisted synthesis, biological evaluation and molecular docking studies of new coumarin-based 1,2,3-triazoles

Author:

Dharavath Ravinder12345,Nagaraju Nalaparaju12345,Reddy M. Ram12345,Ashok D.12345ORCID,Sarasija M.2675,Vijjulatha M.82345,T Vani82345,Jyothi K.910115,Prashanthi G.910115

Affiliation:

1. Green and Medicinal Chemistry Lab

2. Department of Chemistry

3. Osmania University

4. Hyderabad-500007

5. India

6. Satavahana University

7. Karimnagar-505001

8. Molecular Modelling and Medicinal Chemistry Group

9. Department of Pharmaceutical Chemistry

10. St Mary's College of Pharmacy

11. Secunderabad-500025

Abstract

Coumarin-based 1,4-disubstituted 1,2,3-triazole derivatives were synthesized using a highly efficient, eco-friendly protocol via a copper(i)-catalyzed click reaction between various substituted arylazides and terminal alkynes.

Funder

Council of Scientific and Industrial Research, India

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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