One- and two-photon brightness of proteins interacting with gold. A closer look at gold–insulin conjugates

Author:

Bain Dipankar1ORCID,Yuan Hao1,Pniakowska Anna2,Hajda Agata2,Bouanchaud Charlène1,Chirot Fabien1ORCID,Comby-Zerbino Clothilde1,Gueguen-Chaignon Virginie3,Bonačić-Koutecký Vlasta4ORCID,Olesiak-Banska Joanna2,Sanader Maršić Željka45ORCID,Antoine Rodolphe1ORCID

Affiliation:

1. Institut lumière matière, UMR5306, Université Claude Bernard Lyon1-CNRS, Univ. Lyon 69622, Villeurbanne cedex, France

2. Institute of Advanced Materials, Wroclaw University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wroclaw, Poland

3. Université Claude Bernard Lyon 1, CNRS UAR3444, Inserm US8, ENS de Lyon, SFR Biosciences, Lyon 69007, France

4. Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM) at Interdisciplinary Center for Advanced Sciences and Technology (ICAST), University of Split, Poljička cesta 35, 21000 Split, Croatia

5. Faculty of Science, University of Split, Ruđera Boškovića 33, 21000 Split, Croatia

Abstract

By combining experimental studies and time-dependent density functional theory simulations, we show the formation of insulin–Au(iii) conjugates diplaying charge transfer-like excitation in the visible range.

Funder

China Scholarship Council

Agence Nationale de la Recherche

Science and Technology Innovation Plan Of Shanghai Science and Technology Commission

Publisher

Royal Society of Chemistry (RSC)

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