Total syntheses of pyrroloazocine indole alkaloids: challenges and reaction discovery
Author:
Affiliation:
1. Institute of Chemical Research of Catalonia (ICIQ)
2. Barcelona Institut of Science and Technology
3. 43007 Tarragona
4. Spain
5. Departament de Química Analítica i Química Orgànica
Abstract
Total syntheses of pyrroloazocine indole alkaloids (lapidilectines, grandilodines, lundurines and tenuisines) are discussed in terms of existing retrosynthetic solutions and novel reaction discoveries.
Funder
H2020 European Research Council
Ministerio de Economía y Competitividad
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/QO/C7QO00786H
Reference90 articles.
1. Lapidilectine A and lapidilectine B, two new alkaloids from Kopsia lapidilecta
2. Alkaloids of Kopsia lapidilecta
3. Grandilodines A−C, Biologically Active Indole Alkaloids from Kopsia grandifolia
4. Lundurines A–D, cytotoxic indole alkaloids incorporating a cyclopropyl moiety from Kopsia tenuis and revision of the structures of tenuisines A–C
5. Lundurines A, B and C, new indole alkaloids with a novel carbon skeleton containing a cyclopropyl moiety
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