Quantification of clofarabine in urine and plasma by LC-MS/MS: suitable for PK study and TDM in pediatric patients with relapsed or refractory ALL-Reference-Cited by-同舟云学术

Quantification of clofarabine in urine and plasma by LC-MS/MS: suitable for PK study and TDM in pediatric patients with relapsed or refractory ALL

Author:

Zhang Xi¹,Jia Xinbei²³,Tong Weihang⁴,Chen Hui¹,Lei Ning⁴,Li Guangrun¹,Tai Jun²,Li Pengfei¹^ORCID

Affiliation:

1. Pharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongti South Road, Chaoyang District, Beijing, China

2. Department of Otorhinolaryngology, Children's Hospital, Capital Institute of Pediatrics, No. 2 Yabao Road, Chaoyang District, Beijing, China

3. Chinese Academy of Medical Sciences, Peking Union Medical College, No. 30 Shuangqing Road, Haidian District, Beijing, China

4. Pharmacy Department of PLA Rocket Force Characteristic Medical Center, No. 16 Xinwai Street, Xicheng District, Beijing, China

Abstract

Clofarabine is approved for the treatment of relapsed or refractory acute lymphoblastic leukemia (ALL) in pediatric patients aged 1 to 21 years.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

Reference28 articles.

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