Electrochemiluminescence platform for transcription factor diagnosis by using CRISPR–Cas12a trans-cleavage activity-Reference-Cited by-同舟云学术

Electrochemiluminescence platform for transcription factor diagnosis by using CRISPR–Cas12a trans-cleavage activity

Published:2021 Issue:65 Volume:57 Page:8015-8018
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Fan Zhenqiang¹²³⁴⁵^ORCID,Ding Yuedi¹²³⁴⁵,Yao Bo¹²³⁴⁵,Wang Jiaying⁶⁴⁵,Zhang Kai¹²³⁴⁵^ORCID

Affiliation:

1. NHC Key Laboratory of Nuclear Medicine

2. Jiangsu Key Laboratory of Molecular Nuclear Medicine

3. Jiangsu Institute of Nuclear Medicine

4. Wuxi

5. China

6. Drug Clinical Trial Institution, The Affiliated Wuxi People's Hospital of Nanjing Medical University

Abstract

Inhibition of CRISPR–Cas12a activity by target binding to double-stranded DNA (dsDNA) enables detection of NF-κB.

Funder

National Natural Science Foundation of China

Jiangsu Provincial Key Laboratory for Interventional Medical Devices

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC03071J

Reference31 articles.

1. Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB): a new potential therapeutic target in atherosclerosis?

2. The origins of NF-κB

3. Multiple nuclear factors interact with the immunoglobulin enhancer sequences

4. Bicyclic Cyclohexenones as Inhibitors of NF-κB Signaling

5. Combinatorial Selection and Binding of Phosphorothioate Aptamers Targeting Human NF-κB RelA(p65) and p50

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