Quantum chemical (QM:MM) investigation of the mechanism of enzymatic reaction of tryptamine and N,N-dimethyltryptamine with monoamine oxidase A-Reference-Cited by-同舟云学术

Quantum chemical (QM:MM) investigation of the mechanism of enzymatic reaction of tryptamine and N,N-dimethyltryptamine with monoamine oxidase A

Published:2020 Issue:47 Volume:18 Page:9660-9674
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kubicskó Károly¹²³⁴^ORCID,Farkas Ödön⁵¹⁶³⁴^ORCID

Affiliation:

1. Institute of Chemistry

2. Eötvös Loránd University

3. Budapest

4. Hungary

5. Department of Organic Chemistry

6. Eötvös Lorand University

Abstract

Oxidation mechanism pathways of psychedelic N,N-dimethyltryptamine, or the so-called “spirit molecule”, with monoamine oxidase A enzyme were determined.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01118E

Reference122 articles.

1. Identification and Distribution of m-Tyramine in the Rat

2. Tryptamine as an endogenous modulator of neuronal sensitivity to serotonin

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