Aza-BODIPY probe for selective visualization of cyclooxygenase-2 in cancer cells-Reference-Cited by-同舟云学术

Aza-BODIPY probe for selective visualization of cyclooxygenase-2 in cancer cells

Published:2019 Issue:24 Volume:9 Page:13372-13377
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Pewklang Thitima¹²³⁴⁵,Chansaenpak Kantapat⁶⁷⁸⁹,Lai Rung-Yi¹²³⁴⁵,Noisa Parinya¹⁰¹¹¹²³⁴^ORCID,Kamkaew Anyanee¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry

2. Institute of Science

3. Suranaree University of Technology

4. Nakhon Ratchasima

5. Thailand 30000

6. National Nanotechnology Center

7. National Science and Technology Development Agency

8. Thailand Science Park

9. Thailand 12120

10. Laboratory of Cell-Based Assays and Innovations

11. School of Biotechnology

12. Institute of Agricultural Technology

Abstract

A bivalent indomethacin/Aza-BODIPY conjugate can selectively visualize the COX-2 enzyme in cancer and inflamed cells confirming its potential as a COX-2-specific biomarker in clinical applications.

Funder

Suranaree University of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA01948K

Reference50 articles.

1. Cyclooxygenase Enzymes: Regulation and Function

2. Cyclooxygenase 2: a molecular target for cancer prevention and treatment

3. Cyclooxygenase-2 (COX-2) - A Therapeutic Target in Liver Cancer?

4. Inflammation in gastric cancer: Interplay of the COX‐2/prostaglandin E 2 and Toll‐like receptor/MyD88 pathways

5. Cyclooxygenase-2 (COX-2) As a Predictive Marker for the Use of COX-2 Inhibitors in Advanced Non–Small-Cell Lung Cancer

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