Novel 5-chloro-pyrazole derivatives containing a phenylhydrazone moiety as potent antifungal agents: synthesis, crystal structure, biological evaluation and a 3D-QSAR study
Author:
Affiliation:
1. Jiangsu Key Laboratory of Pesticide Science
2. Nanjing Agricultural University
3. Nanjing
4. P. R. China
5. Department of Chemistry
6. College of Sciences
Abstract
Novel 5-chloro-pyrazole derivatives containing a phenylhydrazone moiety were designed and synthesized. Some of the target compounds showed potent fungicidal activity. A 3D-QSAR study provides information for structural optimization.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ00574A
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