Discovery of novel positive allosteric modulators targeting GluN1/2A NMDARs as anti-stroke therapeutic agents-Reference-Cited by-同舟云学术

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Discovery of novel positive allosteric modulators targeting GluN1/2A NMDARs as anti-stroke therapeutic agents

Published:2024 Issue:4 Volume:15 Page:1307-1319
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Zhu Hongyu¹²^ORCID,Chen Xin¹,Zhang Lu³,Liu Xuequan¹²,Chen Ji¹,Zhang Han-Ting¹,Dong Mingxin¹^ORCID

Affiliation:

1. School of Pharmacy, Qingdao University, Qingdao, Shandong, 266021, People's Republic of China

2. Department of Anesthesiology, Affiliated Hospital, Qingdao University, Qingdao, Shandong, 266021, People's Republic of China

3. Department of Clinical Laboratory, Qingdao Women's and Children's Hospital, Qingdao 266034, Shandong Province, China

Abstract

The development of positive allosteric modulators targeting GluN1/2A is a new avenue for neuroprotection.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D3MD00455D

Reference45 articles.

1. Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

2. Ischaemic stroke

3. Calcium, ischemia and excitotoxicity

4. Excitotoxicity and stroke: Identifying novel targets for neuroprotection

5. Targeting NMDA receptors in stroke: new hope in neuroprotection

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