Coupling of amides with ketones via C–N/C–H bond cleavage: a mild synthesis of 1,3-diketones-Reference-Cited by-同舟云学术

Coupling of amides with ketones via C–N/C–H bond cleavage: a mild synthesis of 1,3-diketones

Published:2020 Issue:19 Volume:7 Page:2931-2937
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chen Jiajia¹²³⁴⁵,Xia Yuanzhi⁵⁶⁷⁸^ORCID,Lee Sunwoo¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Chonnam National University

3. Gwangju

4. Republic of Korea

5. College of Chemistry and Materials Engineering

6. Wenzhou University

7. Wenzhou

8. P. R. China

Abstract

Amides react with enolizable ketones to give 1,3-diketones via C–N cleavage of amides and deprotonation of ketones.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00797H

Reference76 articles.

1. A. B. Hughes , Amino Acids, Peptides and Proteins in Organic Chemistry , Wiley , Weinheim , 2011

2. A. Greenberg , C. M.Breneman and J. F.Liebman , The Amide Linkage: Structural Significance in Chemistry, Biochemistry and Materials Science , Wiley-VCH , New York , 2003

3. Breaking Amides using Nickel Catalysis

4. Amide activation: an emerging tool for chemoselective synthesis

5. Amide Activation in Ground and Excited States

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