Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery-Reference-Cited by-同舟云学术

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Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery

Published:2019 Issue:44 Volume:7 Page:6994-7005
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Wang Pengchong¹²³⁴,Yan Yan¹²³⁴,Sun Ying¹²³⁴,Zhang Rui¹²³⁴,Huo Chuanchuan¹²³⁴,Li Lu⁵⁶⁷⁴,Wang Ke¹²³⁴,Dong Yalin⁸⁹⁷⁴^ORCID,Xing Jianfeng¹²³⁴^ORCID

Affiliation:

1. School of Pharmacy

2. Xi’an Jiaotong University

3. Xi’an 710061

4. China

5. Laboratory Animal Center

6. Health Science Center of Xi’an Jiaotong University

7. Xi’an

8. Department of Pharmacy

9. The First Affiliated Hospital of Xi’an Jiaotong University

Abstract

Polydiethylenetriamine is suitable for TAGLN2 siRNA delivery and it have potential for multidrug resistance reversal in human breast cancer.

Funder

National Natural Science Foundation of China

Xi’an Jiaotong University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TB/C9TB01183H

Reference54 articles.

1. Nanoparticle albumin-bound paclitaxel as neoadjuvant chemotherapy of breast cancer: a systematic review and meta-analysis

2. Autophagy facilitates multidrug resistance development through inhibition of apoptosis in breast cancer cells

3. Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2

4. Proteomic analysis of the proteins that are associated with the resistance to paclitaxel in human breast cancer cells

5. Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway

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