Structure–activity relationships of sulfonamides derived from carvacrol and their potential for the treatment of Alzheimer's disease-Reference-Cited by-同舟云学术

Structure–activity relationships of sulfonamides derived from carvacrol and their potential for the treatment of Alzheimer's disease

Published:2020 Issue:2 Volume:11 Page:307-316
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

de Souza Márcia Maria¹²³⁴,Andreolla Marina Corrêa¹²³⁴,Ribeiro Thaís Cecília¹²³⁴,Gonçalves Ana Elisa¹²³⁴,Medeiros Alex Rogério⁵⁶⁷⁸⁹,de Souza Anacleto Silva⁵⁶⁷⁸⁹,Ferreira Leonardo Luiz Gomes⁵⁶⁷⁸⁹,Andricopulo Adriano Defini⁵⁶⁷⁸⁹,Yunes Rosendo Augusto¹⁰¹¹¹²⁴,de Oliveira Aldo Sena⁵⁶⁷⁸⁹^ORCID

Affiliation:

1. School of Health Sciences/Graduate Program in Pharmaceutical Sciences

2. UNIVALI

3. Itajai

4. Brazil

5. Laboratory of Medicinal and Computational Chemistry

6. Center for Research and Innovation in Biodiversity and Drug Discovery

7. Institute of Physics of São Carlos

8. University of Sao Paulo

9. São Carlos

10. Department of Chemistry

11. Federal University of Santa Catarina

12. Florianópolis

Abstract

We investigated the potential of sulfonamides derived from carvacrol as candidates for treatment of Alzheimer's disease. The results are very promising for the molecular target investigated as well as for the phenotypic assays.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/MD/D0MD00009D

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