<scp>d</scp>-<i>chiro</i>-Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition-Reference-Cited by-同舟云学术

d-chiro-Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition

Published:2022 Issue:13 Volume:13 Page:7192-7203
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Yang Qiong¹,Zhang Yao¹,Li Luqi²,Li Jia¹,Li Yunlong³,Han Lin¹^ORCID,Wang Min¹^ORCID

Affiliation:

1. College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, People's Republic of China

2. Life Science Research Core Services, Northwest A&F University, Shaanxi, China

3. Institute of Functional Food of Shanxi, Shanxi Agricultural University, Taiyuan 030006, People's Republic of China

Abstract

DCI promotes adiponectin synthesis in adipose tissue to inhibit high-fat diet-induced obesity in mice and activates the adiponectin-AMPKα/PPARs pathway to regulate hepatic fatty acid metabolism, thereby reducing hepatic lipid deposition.

Funder

Earmarked Fund for China Agriculture Research System

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO00869F

Reference47 articles.

1. Mechanisms, Pathophysiology, and Management of Obesity

2. Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes