A3- and A2B-fluorocorroles: synthesis, X-ray characterization and antiviral activity evaluation against human cytomegalovirus infection-Reference-Cited by-同舟云学术

A3- and A2B-fluorocorroles: synthesis, X-ray characterization and antiviral activity evaluation against human cytomegalovirus infection

Published:2020 Issue:7 Volume:11 Page:783-801
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Kappler-Gratias Sandrine¹²³⁴⁵,Bucher Léo⁶⁷⁸⁹⁵,Desbois Nicolas⁶⁷⁸⁹⁵^ORCID,Rousselin Yoann⁶⁷⁸⁹⁵^ORCID,Bystricky Kerstin¹⁰¹¹¹²¹³¹⁴^ORCID,Gros Claude P.⁶⁷⁸⁹⁵^ORCID,Gallardo Franck¹²³⁴⁵

Affiliation:

1. NeoVirTech

2. SAS

3. Institut des Technologies Avancées en sciences du Vivant (CNRS USR3505)

4. 31106 Toulouse

5. France

6. Institut de Chimie Moléculaire de l'Université de Bourgogne (ICMUB)

7. UMR CNRS 6302

8. Université Bourgogne Franche-Comté

9. 21078 Dijon Cedex

10. Centre de Biologie Intégrative (CBI)

11. Laboratoire de Biologie Moléculaire Eucaryote (LBME)

12. University of Toulouse

13. UPS

14. CNRS

Abstract

New generation of anti hCMV molecules: 29 fluorinated corroles were studied for their antiviral activity evaluation against human cytomegalovirus infection and maximum activity is achieved for A₂B-corroles with SI above 400.

Funder

Centre National de la Recherche Scientifique

Conseil régional de Bourgogne-Franche-Comté

Université de Bourgogne

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/MD/D0MD00127A

Reference43 articles.

1. Herpesvirus DNA polymerases: Structures, functions and inhibitors