An investigation of the antileishmanial properties of semi-synthetic saponins

Author:

Anderson Orlagh1234ORCID,Beckett Joseph1234,Briggs Carla C.1234,Natrass Liam A.12345,Cranston Charles F.1234ORCID,Wilkinson Elizabeth J.6784,Owen Jack H.6784,Mir Williams Rhodri6784,Loukaidis Angelos6784,Bouillon Marc E.6784ORCID,Pritchard Deiniol91084,Lahmann Martina6784ORCID,Baird Mark S.91084ORCID,Denny Paul W.1234ORCID

Affiliation:

1. Department of Biosciences and Centre for Global Infectious Diseases

2. Durham University

3. Durham

4. UK

5. Department of Chemistry and Centre for Global Infectious Diseases

6. Department of Chemistry

7. School of Natural Science

8. Bangor University

9. Naturiol Bangor Ltd

10. Alun Roberts Building

Abstract

Hit anti-leishmanial saponin structures selected following primary and secondary screening.

Funder

Medical Research Council

Innovate UK

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

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