Convergent synthesis and properties of photoactivable NADPH mimics targeting nitric oxide synthases
Author:
Affiliation:
1. PPSM
2. ENS Cachan
3. CNRS
4. Université Paris-Saclay
5. Cachan
6. LBPA
7. Department of Biochemistry
8. University of Texas Health Science Center
9. San Antonio
10. USA
11. Université Paris Saclay
12. INRA UR 892
13. Jouy en Josas
14. France
Abstract
Synthesis, photophysical properties, binding affinity and two-photon fluorescence imaging in living cells of photoactivable NADPH mimics targeting the nitric oxide synthases NADPH binding site are reported.
Funder
National Science Foundation
Agence Nationale de la Recherche
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01533F
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5. NO synthase: Structures and mechanisms
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