Imidazole-modified deferasirox encapsulated polymeric micelles as pH-responsive iron-chelating nanocarrier for cancer chemotherapy-Reference-Cited by-同舟云学术

Imidazole-modified deferasirox encapsulated polymeric micelles as pH-responsive iron-chelating nanocarrier for cancer chemotherapy

Published:2017 Issue:18 Volume:7 Page:11158-11169
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Theerasilp Man¹²³⁴^ORCID,Chalermpanapun Punlop¹²³⁴,Ponlamuangdee Kanyawan¹²³⁴,Sukvanitvichai Dusita¹²³⁴,Nasongkla Norased¹²³⁴^ORCID

Affiliation:

1. Department of Biomedical Engineering

2. Faculty of Engineering

3. Mahidol University

4. Thailand

Abstract

Modified deferasirox encapsulated polymeric micelles demonstrate pH-responsive and ON–OFF release behavior to deplete the iron level in cancer cells. The cellular iron deficiency is a novel strategy for cancer treatment.

Funder

Mahidol University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA26669J

Reference50 articles.

1. Oxidative mechanisms in the toxicity of metal ions

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3. Iron and cancer: more ore to be mined

4. The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and Cancer

5. Iron Chelation in the Treatment of Cancer: A New Role for Deferasirox?

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