Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes-Reference-Cited by-同舟云学术

Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes

Published:2020 Issue:34 Volume:56 Page:4672-4675
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Nödling Alexander R.¹²³⁴^ORCID,Mills Emily M.¹²³⁴,Li Xuefei¹²³⁴,Cardella Davide¹²³⁴,Sayers Edward J.⁵²⁶⁴^ORCID,Wu Shih-Hsiung⁷⁸⁹¹⁰¹¹,Jones Arwyn T.⁵²⁶⁴^ORCID,Luk Louis Y. P.¹²³⁴^ORCID,Tsai Yu-Hsuan¹²³⁴^ORCID

Affiliation:

1. School of Chemistry

2. Cardiff University

3. Cardiff CF10 3AT

4. UK

5. School of Pharmacy and Pharmaceutical Sciences

6. Cardiff

7. Institute of Biological Chemistry

8. Academia Sinica

9. Taipei 11529

10. Taiwan

11. Department of Chemistry

Abstract

Conjugation of small molecules to a simple cyanine dye can lead to organelle-specific delivery.

Funder

Wellcome Trust

Engineering and Physical Sciences Research Council

European Social Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/C9CC07931A

Reference44 articles.

1. Mitochondria as a therapeutic target for common pathologies

2. Mitochondrial diseases

3. Fluorescent probes for organelle-targeted bioactive species imaging

4. Fluorescent Probes for Sensing and Imaging within Specific Cellular Organelles

5. Targeting drugs to mitochondria

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