Design and synthesis of a shikimoyl-functionalized cationic di-block copolypeptide for cancer cell specific gene transfection

Author:

Padhy Abinash1ORCID,Das Pritam23,Mahadik Namita S.23,Panda Sidharth1,Anas Mahammad4,Das Sabyasachi1,Banerjee Rajkumar23ORCID,Sen Gupta Sayam1ORCID

Affiliation:

1. Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal 741246, India

2. Department of Oils, Lipids Science and Technology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India

3. Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Campus, Ghaziabad 201002, India

4. School of Chemical Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, India

Abstract

Targeted and efficient gene delivery systems hold tremendous potential for the improvement of cancer therapy by enabling appropriate modification of biological processes and the strategic design of the delivery vector plays a critical role in the improved efficacy.

Funder

Nano Mission Council

Publisher

Royal Society of Chemistry (RSC)

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