A self-assembled copper-artemisinin nanoprodrug as an efficient reactive oxygen species amplified cascade system for cancer treatment-Reference-Cited by-同舟云学术

A self-assembled copper-artemisinin nanoprodrug as an efficient reactive oxygen species amplified cascade system for cancer treatment

Published:2024 Issue: Volume: Page:
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhu Xueyu¹²³,Bi Chenyang⁴^ORCID,Cao Wei¹²³,Li Shuangshuang¹²³,Yuan Chuting⁴,Xu Pengping⁴^ORCID,Wang Dongdong⁴^ORCID,Chen Qianwang⁴^ORCID,Zhang Lei¹²³

Affiliation:

1. Institute of Clinical Pharmacology, Anhui Medical University, Hefei, 230032, China

2. Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, China

3. Anhui Provincial Key Laboratory of Precision Pharmaceutical Preparations and Clinical Pharmacy, Hefei, 230001, China

4. Hefei National Laboratory for Physical Sciences at Microscale, Department of Materials Science & Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, CAS High Magnetic Field Laboratory, University of Science and Technology of China, Hefei, 230026, China

Abstract

Self-assembled nanoprodrug was constructed via coordinative interactions between artesunate-histidine conjugate and copper ions, serving as efficient Fenton-like reagent for robust ROS generation toward tumor therapy both in vitro and in vivo.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D4TB01237B

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