Homoleptic phosphino copper(i) complexes with in vitro and in vivo dual cytotoxic and anti-angiogenic activity

Author:

Gandin V.123,Trenti A.123,Porchia M.45,Tisato F.45,Giorgetti M.678,Zanusso I.123,Trevisi L.123,Marzano C.123

Affiliation:

1. Dipartimento di Scienze del Farmaco

2. Università di Padova

3. 35131 Padova, Italy

4. IENI-CNR

5. 35127 Padova, Italy

6. Dipartimento di Chimica Industriale

7. Università di Bologna

8. 40136 Bologna, Italy

Abstract

A series of homoleptic phosphino copper(i) complexes inhibit cancer cell growth and angiogenesis in cultured cells and in animal models.

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

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