Low generation PAMAM-based nanomicelles as ROS-responsive gene vectors with enhanced transfection efficacy and reduced cytotoxicity in vitro-Reference-Cited by-同舟云学术

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Low generation PAMAM-based nanomicelles as ROS-responsive gene vectors with enhanced transfection efficacy and reduced cytotoxicity in vitro

Published:2017 Issue:9 Volume:41 Page:3273-3279
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Xu Chen-Tao¹²³⁴⁵^ORCID,Chen Guang¹²³⁴⁵,Nie Xuan¹²³⁴⁵,Wang Long-Hai¹²³⁴⁵,Ding Sheng-Gang⁶⁷⁵⁸,You Ye-Zi¹²³⁴⁵

Affiliation:

1. Key Laboratory of Soft Matter Chemistry

2. Chinese Academy of Sciences

3. Department of Polymer Science and Engineering

4. University of Science and Technology of China

5. Hefei

6. Department of Pediatrics

7. The First Affiliated Hospital of Anhui Medical University

8. China

Abstract

ROS-responsive cationic nanomicelles formed from amphiphilic PPS–SS–PAMAM_G2.0 conjugates exhibit high transfection efficacy and low cytotoxicity.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C6NJ04129A

Reference37 articles.

1. Gene therapy - promises, problems and prospects

2. Gene Therapy That Works

3. Non-viral vectors for gene-based therapy

4. Charged for success

5. Design and development of polymers for gene delivery

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