Immunosuppressive nano-therapeutic micelles downregulate endothelial cell inflammation and immunogenicity-Reference-Cited by-同舟云学术

Immunosuppressive nano-therapeutic micelles downregulate endothelial cell inflammation and immunogenicity

Published:2015 Issue:54 Volume:5 Page:43552-43562
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Nadig Satish N.¹²³⁴⁵,Dixit Suraj K.⁶³⁴⁵⁷,Levey Natalie¹²³⁴⁵,Esckilsen Scott¹²³⁴⁵,Miller Kayla⁶³⁴⁵⁷,Dennis William¹²³⁴⁵,Atkinson Carl⁸³⁴⁵⁹,Broome Ann-Marie⁶³⁴⁵⁷

Affiliation:

1. Department of Surgery

2. Division of Transplant

3. Medical University of South Carolina

4. Charleston

5. USA

6. Department of Radiology & Radiological Science

7. Center for Biomedical Imaging (CBI)

8. Department of Microbiology and Immunology

9. South Carolina Investigators in Transplantation (SCIT)

Abstract

Targeted micelles containing rapamycin (TRaM) suppressed the immune response of IL-8 in oxidatively stressed human umbilical vein endothelial cellsin vitro(a) and accumulated in aorta grafts for transplantation after 6 hours in cold perfusion solution (b).

Funder

American Heart Association

National Center for Advancing Translational Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA04057D

Reference51 articles.

1. Donor and Recipient Contribution to Transplant Vasculopathy in Chronic Renal Transplant Dysfunction

2. Preservation of Kidneys by Machine Perfusion Influences Gene Expression and May Limit Ischemia/Reperfusion Injury