A self-assembling conjugate of SN38 with aminoguanidine for simultaneously suppressing proliferation and migration of breast cancer cells-Reference-Cited by-同舟云学术

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A self-assembling conjugate of SN38 with aminoguanidine for simultaneously suppressing proliferation and migration of breast cancer cells

Published:2024 Issue:35 Volume:48 Page:15590-15598
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Dai Yi¹²,Zhang Yang³,Zhang Yupei¹,Wang Jiamiao¹

Affiliation:

1. College of Pharmaceutical Science, Anhui Xinhua University, Hefei 230088, China

2. Department of Chemistry, University of Science and Technology of China, Hefei 230026, China

3. The First Affiliated Hospital of University of Science and Technology of China, Hefei, 230031, China

Abstract

As an active metabolite of irinotecan, 7-ethyl-10-hydroxy-camptothecin (SN38) exhibits significantly stronger anticancer activity compared to irinotecan.

Funder

National College Students Innovation and Entrepreneurship Training Program

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D4NJ02778G

Reference51 articles.

1. The long story of camptothecin: From traditional medicine to drugs

2. Camptothecin's journey from discovery to WHO Essential Medicine: Fifty years of promise

3. The Mode of SN38 Derivatives Interacting with Nicked DNA Mimics Biological Targeting of Topo I Poisons

4. Comprehensive Pharmacogenetic Analysis of Irinotecan Neutropenia and Pharmacokinetics

5. Extended scaffold glucuronides: en route to the universal synthesis of O-aryl glucuronide prodrugs

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