Synthesis and structure–activity relationship of N4-benzylamine-N2-isopropyl-quinazoline-2,4-diamines derivatives as potential antibacterial agents-Reference-Cited by-同舟云学术

Synthesis and structure–activity relationship of N4-benzylamine-N2-isopropyl-quinazoline-2,4-diamines derivatives as potential antibacterial agents

Published:2017 Issue:82 Volume:7 Page:52227-52237
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jiang Zhengyun¹²³⁴⁵,Hong W. David⁶⁷⁸⁹¹⁰,Cui Xiping¹²³⁴⁵,Gao Hongcan¹²³⁴⁵,Wu Panpan¹²³⁴⁵,Chen Yingshan¹²³⁴⁵,Shen Ding¹²³⁴⁵,Yang Yang¹²³⁴⁵,Zhang Bingjie¹²³⁴⁵,Taylor Mark J.⁶⁷⁸⁹¹⁰,Ward Stephen A.⁶⁷⁸⁹¹⁰,O'Neill Paul M.¹¹¹²⁹¹⁰,Zhao Suqing¹²³⁴⁵^ORCID,Zhang Kun¹²³⁴⁵

Affiliation:

1. Department of Pharmaceutical Engineering

2. School of Chemical Engineering and Light Industry

3. Guangdong University of Technology

4. Guangzhou

5. China

6. Research Centre for Drugs & Diagnostics

7. Department of Parasitology

8. Liverpool School of Tropical Medicine

9. Liverpool

10. UK

11. Department of Chemistry

12. University of Liverpool

Abstract

This paper investigated the SAR of the N⁴-benzylamine-N²-isopropyl-quinazoline-2,4-diamines derivatives with heterocyclic scaffold which showed good activities against S. aureus, E. coli, MRSA, S. epidermidis and S. typhimurium.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA10352B

Reference35 articles.

1. Where will new antibiotics come from?

2. Synthesis, Structure–Activity Relationship Studies, and Antibacterial Evaluation of 4-Chromanones and Chalcones, as Well as Olympicin A and Derivatives

3. Preventing Surgical-Site Infections in Nasal Carriers ofStaphylococcus aureus

4. Synthesis and antibacterial evaluation of a novel series of synthetic phenylthiazole compounds against methicillin-resistant Staphylococcus aureus (MRSA)

5. Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

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