Preparation of Gd-doped AuNBP@mSiO2 nanocomposites for the MR imaging, drug delivery and chemo-photothermal synergistic killing of breast cancer cells

Author:

Tang Shiyi1,Li Ruohan12,Luo Tao1,Huang Tianhao1,Lu Xiaotong1,Wu Xinyao1,Dong Yulin1,Wu Changyu1ORCID,Xu Kai12,Wang Yong12ORCID

Affiliation:

1. School of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China

2. Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, China

Abstract

The fabrication of a Gd-doped AuNBP@mSiO2 nanocomplex for DOX loading, along with NIR laser irradiation, holds significant promise for MR imaging, drug delivery, and effective chemo-photothermal synergistic killing of breast cancer cells.

Funder

National Natural Science Foundation of China

National College Students Innovation and Entrepreneurship Training Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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